satellite cell การใช้

• CD34 and Myf5 markers specifically define the majority of quiescent satellite cells.
• Activated satellite cells initially proliferate as skeletal myoblasts before undergoing myogenic differentiation.
• Satellite cells are described as quiescent myoblasts and neighbor muscle fiber sarcolemma.
• Finally, the muscle fibers that form later arise from satellite cells.
• In response to mechanical strain, satellite cells become " activated ".
• Satellite cell activation has also been demonstrated on an ultrastructural level following exercise.
• MGF expression results in activation of satellite cells and hypertrophy.
• HGF testing is also used to identify active satellite cells.
• Satellite cells are crucial for skeletal muscle adaptation to exercise.
• In addition, satellite cells have the capability to also differentiate into bone or fat.
• To re-activate myogenesis, the satellite cells must be stimulated to differentiate into new fibers.
• While the former induces activation and proliferation, the latter causes differentiation of proliferating satellite cells.
• Activated satellite cells also begin expressing muscle-specific filament proteins such as desmin as they differentiate.
• However, long-term fasting almost completely arrests cell mitosis and decreases the number of satellite cells.
• However, Pax7 is expressed prominently after satellite cell differentiation.
• "Cultured meat " may be produced as strips of satellite cells found in muscle tissue.
• Additionally, satellite cells have been shown to fuse with muscle fibers, developing new muscle fibers.
• Previously untrained muscles acquire newly formed nuclei by fusion of satellite cells preceding the hypertrophy.
• Specifically, it allows a brief pulse of proliferation of these satellite cells in response to injury.
• Wnt plays a crucial role in satellite cell regulation and skeletal muscle aging and also regeneration.